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Tiomolibdate diammonium

CAS No. 15060-55-6

Tiomolibdate diammonium( Ammonium molybdenum sulfide | Ammonium tetrathiomolybdate | ATTM | Coprexa | NSC 286644 )

Catalog No. M27125 CAS No. 15060-55-6

Tiomolibdate diammonium is an inhibitor of superoxide dismutase 1 (SOD1) exerting antiangiogenic and antitumor activities.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Tiomolibdate diammonium
  • Note
    Research use only, not for human use.
  • Brief Description
    Tiomolibdate diammonium is an inhibitor of superoxide dismutase 1 (SOD1) exerting antiangiogenic and antitumor activities.
  • Description
    Tiomolibdate diammonium is an inhibitor of superoxide dismutase 1 (SOD1) exerting antiangiogenic and antitumor activities. Tiomolibdate diammonium inhibits the activities of cuproenzymes, including SOD1 and COX.
  • In Vitro
    ——
  • In Vivo
    Ammonium tetrathiomolybdate(VI) (ATTM) (i.v.; 10?mg/kg) confers significant neuroprotection. Animal Model:Wistar Rats Dosage:10?mg/kg Administration:Intravenous Result:Showed improved functional activity at both 24 h and 7-days post-reperfusion, in parallel with a significant reduction in infarct size.
  • Synonyms
    Ammonium molybdenum sulfide | Ammonium tetrathiomolybdate | ATTM | Coprexa | NSC 286644
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Apoptosis| ERK1| ERK2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    15060-55-6
  • Formula Weight
    260.27
  • Molecular Formula
    H8MoN2S4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 5 mg/mL (19.21 mM)
  • SMILES
    [NH4+].[NH4+].[S-][Mo]([S-])(=S)=S
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hanna Piotrowska, et al. DMU-212 inhibits tumor growth in xenograft model of human ovarian cancer. Biomed Pharmacother. 2014 May;68(4):397-400.
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